|
Accession number;99A0228217
|
| Title;Enantiomeric Electron Transfer Reaction of Azurin(I) with the Optically Active Ruthenium(III) Complexes. |
| Author;
KUMITA HIDEYUKI
(Nagoya Inst. of Technol.)
ASAI NOBUO
(Nagoya Inst. of Technol.)
SAKURAI TAKESHI
(Fac. of Pharm. Sci., Kanazawa Univ.)
JITSUKAWA KOICHIRO
(Nagoya Inst. of Technol.)
MASUDA HIDEKI
(Nagoya Inst. of Technol.)
EINAGA HISAHIKO
(Nagoya Inst. of Technol.)
|
Journal Title;Abstracts. Symposium on Biofunctional Chemistry
|
Journal Code:L0836A
|
ISSN:
|
|
VOL.13th;NO.;PAGE.85-87(1998)
|
| Figure&Table&Reference; |
| Pub. Country;Japan |
| Language;Japanese |
| Abstract;With a view to understanding the electron transfer and molecular recognition mechanisms in azurin, the kinetics of the electron transfer reaction with the Ru(III) complexes of optically active amino acids was investigated by a stopped-flow spectrophotometric method. In the rate constants, two interesting structural features were observed: (i) The Ru(III) complexes with aromatic amino acids (L-phenylalarine derivative) exhibited larger rate constants than those with aliphatic ones (L-alanine and L-leusine derivatives), furthermore, (ii) the complex with D-phenylalanine derivative indicated significantly larger rate constant than L-phenylalanine derivative. The above findings suggest that the electron transfer reaction in azurin have both site-specificity and enantio-selectivity. (author abst.) |
|
|
|
Related Articles;
|
