Neoadjuvant Chemotherapy for Advanced Cervical Cancer.
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Accession number;99A0203858
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| Title;Neoadjuvant Chemotherapy for Advanced Cervical Cancer. |
| Author;
KODAMA JUN'ICHI
(Okayama Univ., Sch. of Med.)
IKUHASHI HIROMI
(Okayama Univ., Sch. of Med.)
HONGO ATSUSHI
(Okayama Univ., Sch. of Med.)
MIZUTANI YASUSHI
(Okayama Univ., Sch. of Med.)
MIYAGI YASUNARI
(Okayama Univ., Sch. of Med.)
YOSHINOUCHI MITSUO
(Okayama Univ., Sch. of Med.)
KOBASHI YUJI
(Okayama Univ., Sch. of Med.)
OKUDA HIROYUKI
(Okayama Univ., Sch. of Med.)
KUDO TAKAFUMI
(Okayama Univ., Sch. of Med.)
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Journal Title;Japanese Journal of Cancer and Chemotherapy
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Journal Code:Z0938A
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ISSN:0385-0684
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VOL.26;NO.1;PAGE.89-92(1999)
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| Figure&Table&Reference;FIG.1, TBL.5, REF.15 |
| Pub. Country;Japan |
| Language;Japanese |
| Abstract;Twenty-five patients with advanced cervical cancer (IIb-IVa) were treated with neoadjuvant chemotherapy followed by radical hysterectomy or radiotherapy. According to the evaluation by MRI, complete response ws achieved in 2 cases and partial response in 17 cases. Eventually the response rate was 76%. The response rate was higher in squamous cell carcinomas (85%) than adenocarcinomas or adenosquamous carcinomas (67%). The histological effect is superior in squamous cell carcinomas than adenocarcinomas or adenosqueamous carcinomas. Radical hysterectomy was performed in 5 cases of 11 (45%) stage III-IVa cervical cancers. There was no correlation between tumor size and response to NAC. NAC therapy may be useful therapy in advanced cervical cancers, especially squamous cell carcinomas. (author abst.) |
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