A Report of Two Cases Suggesting Positive Influence of Pregnancy on Uveitis Activity.
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Accession number;99A0207602
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| Title;A Report of Two Cases Suggesting Positive Influence of Pregnancy on Uveitis Activity. |
| Author;
TAGUCHI CHIKAKO
(Kurume Univ., Fac. of Med.)
IKEDA EIKO
(Kurume Univ., Fac. of Med.)
HIKITA NAOFUMI
(Kurume Univ., Fac. of Med.)
MOCHIZUKI MANABU
(Kurume Univ., Fac. of Med.)
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Journal Title;Journal of Japanese Ophthalmological Society
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Journal Code:Z0666A
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ISSN:0029-0203
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VOL.103;NO.1;PAGE.66-71(1999)
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| Figure&Table&Reference;FIG.3, TBL.2, REF.24 |
| Pub. Country;Japan |
| Language;Japanese |
| Abstract;Background: Little is known about the influence of pregnancy on uveitis activity. We report two cases suggesting a favorable influence of pregnancy on the clinical course of uveitis. Case: A 30-year-old woman who was three months pregnant was suspected Vogt-Koyanagi-Harada disease based on the systemic symptoms and ocular findings of iritis and multi-focal serous retinal detachment. She was positive to human leukocyte antigen(HLA)-DR4. She was treated only with topical corticosteroids. One month later, the retinal detachment disappeared. Six month later, a healthy baby was born. The fundus of both eyes took on a sunset glow appearance and there has been no recurrence of uveitis. The other case was a 23-year-old woman with Behcet's disease who had several episodes of uveitis in a year even on tacrolimus. Because of pregnancy, all systemic drugs including tacrolimus were discontinued since then. Interestingly, the frequency of uveitis was remarkably decreased during the pregnancy. A normal healthy baby was born. The uveitis has almost completely disappeared since parturition until now. Conclusion: It is considered that the increase of intrinsic hormone, especially corticosteroid, and some other factors with pergnancy may give the suppressive influence on uveitis in our cases. (author abst.) |
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