Treatment with 5-FU Modulated by Low-dose CDDP for Advanced Cancers and Recurrent Cases of Metastasis.

Accession number;99A0286468
Title;Treatment with 5-FU Modulated by Low-dose CDDP for Advanced Cancers and Recurrent Cases of Metastasis.
Author; SHINKAI KIYOTO (Ureshino National Hospital) KIDA HARUMI (Ureshino National Hospital) HISANO HIROSHI (Ureshino National Hospital) SHIBASAKI SHIN'ICHI (Ureshino National Hospital) YANO HIROSHI (Ureshino National Hospital) NOMURA MASAHITO (Ureshino National Hospital)
Journal Title;Japanese Journal of Cancer and Chemotherapy
Journal Code:Z0938A
ISSN:0385-0684
VOL.26;NO.3;PAGE.329-332(1999)
Figure&Table&Reference;TBL.5, REF.7
Pub. Country;Japan
Language;Japanese
Abstract;Advanced gastric, colon and esophageal cancers(n=21) were treated with 5-FU(250mg) modulated by CDDP(5mg). The reductive ratio of tumor was 6/21(28.6%). Six cases of partial response(PR) were limited with no surgical treatment and exploratory laparotomy of all cases, and the effectiveness rate was 54.5%(6/11). Few side effects, such as dysfunction of bone marrow and kidney, were noted. Even if side effects occurred, they were mild. We concluded that excellent treatment with 5-FU modulated by CDDP has markedly improved the efficacy. (author abst.)
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