A Case of Cerebral Juvenile Pilocytic Astrocytoma: Observation of the Development of the Tumor.

Accession number;99A0326275
Title;A Case of Cerebral Juvenile Pilocytic Astrocytoma: Observation of the Development of the Tumor.
Author; SUGIYAMA KAZUHIKO (Hiroshima Univ., Sch. of Med.) KURISU KAORU (Hiroshima Univ., Sch. of Med.) ARITA KAZUNORI (Hiroshima Univ., Sch. of Med.) OBA SHINJI (Hiroshima Univ., Sch. of Med.) MIZOUE TATSUYA (Hiroshima Univ., Sch. of Med.) HARADA KUNIO (Hiroshima Univ., Sch. of Med.) SADATOMO TAKASHI (Hiroshima Univ., Sch. of Med.) YOSHIOKA HIROYUKI (Hiroshima Univ., Sch. of Med.) UOZUMI TOORU (Hiroshima Prefect. Hosp.)
Journal Title;Brain Nerve
Journal Code:Z0685A
ISSN:0006-8969
VOL.51;NO.2;PAGE.149-153(1999)
Figure&Table&Reference;FIG.3, REF.17
Pub. Country;Japan
Language;Japanese
Abstract;A case with cerebral juvenile pilocytic astrocytoma(JPA) was reported. The patient was 33-month-old boy, who developed headache and loss of activity on December, 1994. Although he was indicated macrocephaly at the age of just 1 year, CT scan showed no abnormality at that time. On admission, MRI revealed multiple large cysts with an enhanced mural nodule in the left frontal lobe. The tumor was totally removed, and histologically diagnosed as JPA, because of alternating two types of structures of loose knit tissue composed of satellite astrocytes and compact tissue consisting of highly fibrillate cells. MIB-1 percent positivity was almost negative. We summarized and discussed the clinicopatho-logical and proliferating characteristics of the cerebral JPA. These considerations suggested that the tumor already existed at the age of 1 year and developed during these 20 months, according to the theory that the growth rate of JPAs is programmed to slow down as the ptient grows. (author abst.)
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