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Accession number;99A0183164
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| Title;Sinus bradycardia induced by talipexole hydrochloride in a patient with Parkinson disease. |
| Author;
SAKAI TOSHIYUKI
(Saiseikai Matsuzaka Gen. Hosp.)
II YUICHIRO
(Saiseikai Matsuzaka Gen. Hosp.)
KUZUHARA SHIGEKI
(Mie Univ.)
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Journal Title;Clinical Neurology
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Journal Code:Z0689A
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ISSN:0009-918X
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VOL.38;NO.8;PAGE.771-775(1998)
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| Figure&Table&Reference;FIG.3, REF.8 |
| Pub. Country;Japan |
| Language;Japanese |
| Abstract;We report sinus bradycardia induced by talipexole hydrochloride in a 65-year-old man with Parkinson disease. Approximately four hours after he had taken 0.8mg of talipexole hydrochloride, he acutely developed sleepiness, delusion, akinesia, and faintness associated with hypotension and sinus bradycardia. Another similar episode occurred when he had taken talipexole hydrochrolide 1.2mg/day in combination with a daily dose of 200mg of levodopa and 20mg of carbidopa. These symptoms persisted for 12 hours and diminished gradually without any specific treatments. Talipexole hydrochloride, a stimulator of both the D2 and .ALPHA.2 receptors probably induced bradycardia and hypotension in the present case. (author abst.) |
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