The Efficacy of Oral Vitamin A Supplementation for Measles and Respiratory Syncytial Virus(RSV) Infection.
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Accession number;99A0385869
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| Title;The Efficacy of Oral Vitamin A Supplementation for Measles and Respiratory Syncytial Virus(RSV) Infection. |
| Author;
KAWASAKI YUKIHIKO
(Fukushimaken'idai I)
HOSOYA MITSUAKI
(Fukushimaken'idai I)
KATAYOSE MASAHIKO
(Koritsu Soma Sogo Byoin)
SUZUKI HITOSHI
(Fukushimaken'idai I)
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Journal Title;Journal of the Japanese Association for Infectious Diseases
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Journal Code:Z0760A
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ISSN:0387-5911
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VOL.73;NO.2;PAGE.104-109(1999)
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| Figure&Table&Reference;TBL.4, REF.19 |
| Pub. Country;Japan |
| Language;Japanese |
| Abstract;Recentry, the efficacy of oral vitamin A supplementation for measles and respiratory syncytial (RSV) infection has been evaluated in developing countries. However, in developed countries where vitamin A defiency is little worth consideration, few studies have been conducted on the effect of vitamin A supplementation. The effect of oral vitamin A (100,000IU) supplementation was evaluated in 105 children with measles (age 5 months to 4 years) and in 96 children with RSV infection (ages a month to 2.5 years) in Fukushima, Japan. Comparisons were made of clinical signs, duration of hospitalization and complications between treated groups and non-treated groups. Treated group (measles n=47, RSV n=54) and non-treated groups (measles n=58, RSV n=42) had similar baseline characteristics. Patients with measles given a vitamin A supplementation had a shorter duration of cough (7.2.+-.1.6 vs 9.2.+-.1.8 days, p<0.05) and patients with severe RSV infection given a vitamin A supplementation had a shorter duration of retraction (3.6.+-.1.4 vs 5.3.+-.0.8 days, p<0.05) and wheezing (4.4.+-.1.7 vs 6.3.+-.1.5 days, p<0.05). Toxicities, including excess vomiting and bulging fontanel were not observed. Our findings may suggest the efficacy of oral vitamin A supplementation for measles and severe RSV infection, in children who have no malnutrition. (author abst.) |
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