Computed Tomography with Normal Chest Radiography in Childhood Tuberculosis.

Accession number;99A0385872
Title;Computed Tomography with Normal Chest Radiography in Childhood Tuberculosis.
Author; KATAKURA SHIGEKI (Yokohama City Univ., Sch. of Med.) IMAGAWA TOMOYUKI (Yokohama City Univ., Sch. of Med.) ITO SHUICHI (Yokohama City Univ., Sch. of Med.) MIYAMAE TAKAKO (Yokohama City Univ., Sch. of Med.) MITSUDA TOSHIHIRO (Yokohama City Univ., Sch. of Med.) IBE MASAAKI (Yokohama City Univ., Sch. of Med.) AIHARA YUKO (Yokohama City Univ., Sch. of Med.) YOKOTA SHUMPEI (Yokohama City Univ., Sch. of Med.)
Journal Title;Journal of the Japanese Association for Infectious Diseases
Journal Code:Z0760A
ISSN:0387-5911
VOL.73;NO.2;PAGE.130-137(1999)
Figure&Table&Reference;FIG.5, REF.9
Pub. Country;Japan
Language;Japanese
Abstract;During the recent 2 years we experienced 5 children (2 months-5 years old) with lung tuberculosis, all of whom had positive tuberculin skin-tests, and were in close contact with their family members who had active tuberculosis. However, no abnormal findings on chest X-ray films were pointed out by 2 independent roentogenologists, and no increased levels of inflammatory markers including WBC numbers, CRP, and ESR were detected in all but one child. Moreover, mycobacterial examination of sputa and/or gastric aspirates by microscope, culture technique, and PCR amplification revealed no causative bacilli in 4 children. To clarify whether these children were affected by Mycobacterium tuberculosis, chest CT scan was applied. Surprisingly, all 5 children were revealed to have abnormal changes including primary complexes in the lung field. Taken together, it is important to pursuit the apparent lung tuberculosis in children with a positive family history and positive tuberculin skin-test. (author abst.)
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