Relationship Between Preference for 0.9% NaCl Solution and Salt Taste Threshold in Male Closed Colony (ICR) Mice.
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Accession number;99A0412430
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| Title;Relationship Between Preference for 0.9% NaCl Solution and Salt Taste Threshold in Male Closed Colony (ICR) Mice. |
| Author;
ICHIJO YUKA
(Kyorin Univ., Sch. of Health Sci.)
DEJIMA YASUSHI
(Kyorin Univ., Sch. of Health Sci.)
TAKASAKA KOICHI
(Kyorin Univ., Sch. of Health Sci.)
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Journal Title;Journal of Japanese Society of Nutrition and Food Science
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Journal Code:F0624A
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ISSN:0287-3516
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VOL.52;NO.2;PAGE.97-101(1999)
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| Figure&Table&Reference;FIG.3, REF.17 |
| Pub. Country;Japan |
| Language;Japanese |
| Abstract;Male closed colony (ICR) mice were examined for their taste preference for 0.9% NaCl solution (0.9% preference) and salt taste threshold by the two-bottle test. The 0.9% preference was indicated as the relative intake of 0.9% NaCl solution to total fluid intake (sum of distilled water and 0.9% NaCl solution). The mean value and standard deviation (SD) of 0.9% preference in 332 mice was 45.5% and 19.1, respectively. The preference ranged from 4.2% to 94.5%, and was shown to have a normal distribution by the Kolmogorov-Smirnov test. The salt taste threshold was tested in 61 mice divided into 3 groups according to the strength of 0.9% preference, i.e., 64.6% (mean+SD) and over (Group H), less than 26.4% (mean-SD) (Group L), and others (Group M) . In the threshold test, the concentration of NaCl solution in one of the two bottles was raised from 0.0016% to 0.4% stepwise every two days. The threshold in Group H (0.0125%) was lower than that in Group M (0.05%). The threshold in Group L could not be defined, and was considered to exist at a concentration higher than 0.4%. These results indicate that individual difference is related to taste threshold, and could be an effective factor when male closed colony (ICR) mice are used in controlled studies of salt taste. (author abst.) |
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