Pregnancy-Associated Osteoporosis with Elevated Levels of Circulating Parathyroid Hormone-Related Protein: A Report of Two Cases.

Accession number;99A0225430
Title;Pregnancy-Associated Osteoporosis with Elevated Levels of Circulating Parathyroid Hormone-Related Protein: A Report of Two Cases.
Author; ANAI T (Oita Medical Univ., Oita, Jpn) TOMIYASU T (Oita Medical Univ., Oita, Jpn) ARIMA K (Oita Medical Univ., Oita, Jpn) MIYAKAWA I (Oita Medical Univ., Oita, Jpn)
Journal Title;J Obstet Gynaecol Res
Journal Code:Y0696A
ISSN:1341-8076
VOL.25;NO.1;PAGE.63-67(1999)
Figure&Table&Reference;FIG.2, TBL.1, REF.22
Pub. Country;Japan
Language;English
Abstract;Two lactating women who had complained of back pain developed spontaneous vertebral fractures with low bone mineral density (BMD) several months postpartum. The back pain and biochemical abnormalities presented as hypercalcemia and elevated plasma levels of the parathyroid hormone-related protein (PTH-rP) that returned to normal indices with increasing BMD after weaning. The increased circulating PTH-rP might contribute to the pregnancy-associated osteoporosis in women who probably are already osteopenic. (author abst.)
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