Assessment of unilateral hydronephrosis by contralateral compensatory hypertrophy.

Accession number;99A0299759
Title;Assessment of unilateral hydronephrosis by contralateral compensatory hypertrophy.
Author; MIYAZATO MINORU (Tokyo Metrop. Kiyose Child. Hosp.) NAKAI HIDEO (Tokyo Metrop. Kiyose Child. Hosp.) SASAKI HITOMI (Tokyo Metrop. Kiyose Child. Hosp.) HIGUCHI AKIHIRO (Tokyo Metrop. Kiyose Child. Hosp.) IZUMITANI MASANOBU (Tokyo Metrop. Kiyose Child. Hosp.) SHISHIDO SEIICHIRO (Tokyo Metrop. Kiyose Child. Hosp.) GOTO TAKAFUMI (Tokyo Metrop. Kiyose Child. Hosp.) KAWAMURA TAKESHI (Tokyo Metrop. Kiyose Child. Hosp.) OGAWA YOSHIHIDE (Univ. of Ryukyus, Fac. of Med.)
Journal Title;Nishinihon Journal of Urology
Journal Code:Z0253B
ISSN:0029-0726
VOL.61;NO.2;PAGE.97-102(1999)
Figure&Table&Reference;FIG.7, TBL.2, REF.12
Pub. Country;Japan
Language;Japanese
Abstract;Unilateral hydronephrotic renal dysfunction could be evaluated by contralateral compensatory hypertorphy. The appropriateness of the present evaluation with intravenous pyelography(IVP), diuretic renogram, and pressure flow study was verified. Furthermore, we investigated whether or not we can use compensatory hypertrophy in the diagnosis of hydronephrosis. Eighty-four patients with unilateral hydronephrosis who visited our Division of Urology between 1977 and 1995 were divided into three groups: nephrectomy-7 children; pyeloplasty-56 children; observed conservatively-21 children. The contralateral renal axial length was measured by the nephrogram of IVP (or ultrasonography), and plotted on the normal renal growth curve. 1. The compensatory hypertrophy of the follow-up group was lower than that of the surgery group (p<0.05). 2. On the other hand, it was lower in the surgery group among children under one year of age (p<0.01). 3. However, some of the follow-up group tended to demonstrate progressive compensatory hypertrophy even though no obvious renal dysfunction was noted (p<0.1). From the viewpoint of compensatory hypertrophy, early discovery and treatment would seem to be essential. Moreover, contralateral compensatory hypertrophy and hydronephrotic renal dysfunction would seem to be correlated. Unexpectedly, some of the observation cases, which had formerly been diagnosed as equivocal from the diuretic renogram, showed progressive compensatory hypertrophy, suggesting our conventional diagnostic procedures to be somewhat inadequate. Our findings suggest that we can utilize compensatory hypertrophy in the diagnosis of hydronephrosis among neonates and infants. (author abst.)