Coefficient of variations of the R-R interval in hemodialysed patients.

Accession number;99A0299760
Title;Coefficient of variations of the R-R interval in hemodialysed patients.
Author; SUGAYA KIMIO (Univ. of Ryukyus, Fac. of Med.) ODA MASAMI (Univ. of Ryukyus, Fac. of Med.) ASHITOMI KATSUHIRO (Univ. of Ryukyus, Fac. of Med.) GOYA MASATO (Univ. of Ryukyus, Fac. of Med.) MIYAZATO MINORU (Univ. of Ryukyus, Fac. of Med.) YONO HIROYUKI (Univ. of Ryukyus, Fac. of Med.) SUNABE TSUYOSHI (Univ. of Ryukyus, Fac. of Med.) MIYAZATO TOMONORI (Univ. of Ryukyus, Fac. of Med.) OGAWA YOSHIHIDE (Univ. of Ryukyus, Fac. of Med.)
Journal Title;Nishinihon Journal of Urology
Journal Code:Z0253B
ISSN:0029-0726
VOL.61;NO.2;PAGE.103-107(1999)
Figure&Table&Reference;FIG.8, REF.8
Pub. Country;Japan
Language;Japanese
Abstract;We studied the influence of hemodialysis on parasympathetic nerve function by comparing the coefficient of variations of the R-R interval(CVR-R) in 17 healthy subjects (control group), in 11 chronically hemodialysed patients without diabetes mellitus (non-DM-HD group) and in 12 chronically hemodialysed patients with diabetes mellitus (DM-HD group). In the control group, the CVR-R (y) was correlated reversely with age (x) (y=-0.093x+8.61, p<0.01). When the ages of the subjects in each group were limited to 60 years and over, there no significant differences in the mean CVR-R among the three groups. When the ages of the subjects in each group were limited to 59 years and under, the mean CVR-R of both the non-DM-HD group (3.17+2.13%) and the DM-HD group (2.23.+-.2.04%) was significantly (p<0.05, p<0.01, respectively) low compared with that of the control group (5.08.+-.1.65%). There was no correlation between the CVR-R and the period of hemodialysis in either the non-DM-HD group or the DM-HD group. In the non-DM-HD group, the CVR-R (2.73.+-.1.63%) was significantly decreased (1.84.+-.0.67%) after a four-hour period of hemodialysis. In the DM-HD group, the CVR-R did not change during the four-hour period of hemodialysis, perhaps because the CVR-R (1.76.+-.1.40%) prior to hemodialysis in the DM-HD group was already comparatively low and nearly equal to that after hemodialysis in the non-DM-HD group. Therefore, hemodialysis may transiently suppress the parasympathetic nerve function, however, it may not be able to suppress the parasympathetic nerve function in diabetic patients whose parasympathetic nerve function is already damaged. (author abst.)