Primary hepatic carcinoid tumor.

Accession number;99A0327138
Title;Primary hepatic carcinoid tumor.
Author; ASAKAWA T (Nagasaki Univ. School Of Medicine, Nagasaki, Jpn) TOMIOKA T (Nagasaki Univ. School Of Medicine, Nagasaki, Jpn) ABE K (Nagasaki Univ. School Of Medicine, Nagasaki, Jpn) YAMAGUCHI T (Yurino Hospital, Nagasaki, Jpn) TSUNODA T (Kawasaki Medical School, Kurashiki, Jpn) KANEMATSU T (Nagasaki Univ. School Of Medicine, Nagasaki, Jpn)
Journal Title;J Gastroenterol
Journal Code:Z0748A
ISSN:0944-1174
VOL.34;NO.1;PAGE.123-127(1999)
Figure&Table&Reference;FIG.3, REF.20
Pub. Country;Japan
Language;English
Abstract;A primary hepatic carcinoid tumor arising in a 49-year-old woman is reported. The patient was admitted with multiple hepatic tumors and treated by a left lobectomy and cholecystectomy. Cut sections of the specimen revealed a solid and necrotic mass, measuring 10 * 12 * 13 cm, with multiple small satellite nodules. Histologically, the tumor cells had small oval-shaped nuclei and presented with a trabecular arrangement and rosette-like formation. Both Grimelius and Fontana-Mason stainings were positive. The tumor cells were positive for chromogranin A and negative for other antigens. Ultrastructural studies of the tumor cells revealed duct-like formation with microvilli and a cluster of dense small immature neurosecretory granules in the cytoplasm. These findings were consistent with those of carcinoid tumors. Postoperatively, the patient was treated with repeated transcatheter arterial chemoembolization for any remnant tumors. However, she died of the disease 5 years after the initial surgery. The autopsy findings suggested the primary site to be the liver. (author abst.)
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