An Evaluation of Compliance for .ALPHA.-glucosidase Inhibitor

Accession number;99A0450024
Title;An Evaluation of Compliance for .ALPHA.-glucosidase Inhibitor
Author; YAMAOKA KEIKO (Teikyo Univ., Hosp.) FUKUZUMI SHIGEYASU (Teikyo Univ., Hosp.) YOSHIZUMI KAZUTOSHI (Teikyo Univ., Hosp.) IGUCHI EMIKO (Teikyo Univ., Hosp.) SASAKI MARIKO (Teikyo Univ., Hosp.) NAKAJIMA YASUO (Teikyo Univ., Hosp.) YAMAUCHI TOSHIKAZU (Teikyo Univ., Sch. of Med.)
Journal Title;Japanese Journal of Hospital Pharmacy
Journal Code:Y0888A
ISSN:0389-9098
VOL.25;NO.2;PAGE.204-211(1999)
Figure&Table&Reference;FIG.7, TBL.1, REF.5
Pub. Country;Japan
Language;Japanese
Abstract;We conducted a questionnaire surver of 164 outpatient; who had been prescribed either voglibose or acarbose as an .ALPHA.-glucosidase inhibitor(.ALPHA.-GI) about their knowledge of the medicine, the conditions for taking this medicine, the adverse reactions and symptoms, and also of patient who took another medicine to lower blood sugar level together with .ALPHA.-GI. Regarding the patients knowledge regarding the name of the medicine, .ALPHA.-GI, was low, namely 23.8%. But 82.9% of them complier with the prescription by taking it just before meals. About 71% of them complained of the digestive symptoms such as fletulation. The symptoms also different between the two medicines. Of the 135 patients who took the medicine three times a day, 78.5% toox it at noon. The rate was more than 10% lower than that of the patients who took it in the morning and the evening. A total of 119 patients(72.6%) took another medicine to lower their blood sugar together with it. Half of them took sulfonyl ureas, and of the patients who took the two medicines, 42.9% against lowering bloood sugar while 28.8% of them correct glucose substitutes. In addition 33.9% of them had a history of low blood sugar. In this investigation, the two .ALPHA.-GI medicines produced differences in both the use and the occurrence of adverse reactions. (author abst.)