Slowly progressive aphemia. A case report.

Accession number;99A0264702
Title;Slowly progressive aphemia. A case report.
Author; IWASAKI TAKAYUKI (Tokyo Med. and Dent. Univ.) SAITO YUKINOBU (Fed. of Natl. Public Serv. and Affil. Personnel Mutual Aid Assoc., Yokosuka Hosp.) WADA YOSHIAKI (Tokyo Med. and Dent. Univ.) ISHIAI SUMIO (Tokyo Metrop. Inst. for Neurosci.) ISHII KENJI (Tokyo Metrop. Inst. of Gerontology)
Journal Title;Clinical Neurology
Journal Code:Z0689A
ISSN:0009-918X
VOL.38;NO.9;PAGE.801-805(1998)
Figure&Table&Reference;FIG.2, TBL.2, REF.19
Pub. Country;Japan
Language;Japanese
Abstract;A 69-year-old women was admitted to Tokyo Medical and Dental University Hospital because of slowly progressive difficulty in speech production over 8-years. On admission, her spontaneous speech was non-fluent, limited to one-syllable utterance, and severely efforty. But her visual and auditory comprehension was preserved. There was no significant general intellectual deterioration. Severe buccofacial apraxia, but no swallowing was observed. So we considered her difficulty in speech as aphemia. Three-dimensionally reconstructed surface MR image clearly showed severe atrophy in the posterior part of the left inferior frontal gyrus and the lower part of the left pre-central gyrus. The FDG-PET demonstrated a focal hypometabolism in the same region. The lesion in this area was suggested to be a cause of speech production difficulty in this case. (author abst.)
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