Science Links Japan | A case of atypical Guillain-Barre syndrome exclusively showing multiple cranial nerve palsy with an elevation of anti-GQ1b and anti-GT1a IgG antibodies.

A case of atypical Guillain-Barre syndrome exclusively showing multiple cranial nerve palsy with an elevation of anti-GQ1b and anti-GT1a IgG antibodies.

Accession number;99A0264710

Title;A case of atypical Guillain-Barre syndrome exclusively showing multiple cranial nerve palsy with an elevation of anti-GQ1b and anti-GT1a IgG antibodies.

Author; OHORI NOBUHIRA (Japan Red Cross Soc. Hiroshima Atom. Bomb Hosp.) KUSUNOKI SUSUMU (Univ. of Tokyo, Fac. of Med.) OTA MICHIYA (Japan Red Cross Soc. Hiroshima Atom. Bomb Hosp.)

Journal Title;Clinical Neurology

Journal Code:Z0689A

ISSN:0009-918X

VOL.38;NO.9;PAGE.843-845(1998)

Figure&Table&Reference;FIG.1, TBL.1, REF.10

Pub. Country;Japan

Language;Japanese

Abstract;This is a case report of atypical Guillain-Barre syndrome(GBS). A 42-year-old woman displayed pharyngeal paralysis after a mild upper respiratory infection, subsequently having developed ophthalmoplegia, facial diplegia and accessory nerve palsy within about ten days. She had neither weakness nor abnormal tendon reflexes in the extremities. During the acute phase of the disease we found significant elevation of anti-GQ1b and anti-GT1a IgG antibodies in the serum, and immunoadsorption therapy had a remarkable effect on the symptoms. Although our case was extremely atypical of GBS in terms of exclusively showing multiple cranial nerve palsy and lacking areflexia, the elevation of anti-glycolipid antibodies during the acute phase suggests that this case shares pathogenesis with GBS. (author abst.)

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