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Accession number;99A0300740
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| Title;A Case of Pancreatic Diabetes due to Hypoplasia of the Dorsal Pancreas. |
| Author;
TANAKA KIYONOBU
(Saijochuobyoin)
TAKADA YASUHARU
(Saijochuobyoin)
MATSUNAKA TSUYOSHI
(Saijochuobyoin)
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Journal Title;Journal of the Japan Diabetic Society
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Journal Code:Z0279B
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ISSN:0021-437X
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VOL.42;NO.1;PAGE.43-47(1999)
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| Figure&Table&Reference;FIG.3, TBL.2, REF.10 |
| Pub. Country;Japan |
| Language;Japanese |
| Abstract;We report a case of diabetes mellitus associated with hypoplasia of the dorsal pancreas. The patient was a 73-year-old woman. She was admitted to our hospital for the purpose of controlling diabetes mellitus on July 10, 1997. Fasting blood glucose level was 145mg/dl and HbA1c was 7.3% on admission. Her pancreatic body and tail could not be demonstrated on an abdominal ultrasonogram or CT scan. Endoscopic retrogradecholangiopancreatogram showed that the main pancreatic duct was extremely shortened and tapered. From these results, she was diagnosed as having aplasia of the dorsal pancreas. On further examination by calculating from the rate of urinary C-peptide excretion, her insulin secretion was found to be severely decreased. However, the peak concentration of plasma C-peptide following a glucagon loading test was higher than those of insulindependent diabetic patients with the same level of basal concentration of plasma C-peptide. In addition, her insulin sensitivity (85mg/dl) was normal, as measured by the steady-state of plasma glucose method. These results suggest that diabetes mellitus in this patient is caused by islet hypoplasia of the pancreas, a condition which does not necessarily predispose to diabetes. (author abst.) |
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