Amelioration of Acromegaly after Pituitary Infarction Due to Gastrointestinal Hemorrhage from Gastric Ulcer.

Accession number;99A0439791
Title;Amelioration of Acromegaly after Pituitary Infarction Due to Gastrointestinal Hemorrhage from Gastric Ulcer.
Author; IMAKI T (Tokyo Women's Medical Coll., Tokyo, Jpn) YAMADA S (Toranomon Hospital, Tokyo, Jpn) HARADA S (Tokyo Women's Medical Coll., Tokyo, Jpn) TSUCHIYA M (Tokyo Women's Medical Coll., Tokyo, Jpn) SANO T (Univ. Tokushima, Tokushima, Jpn) DEMURA H (Tokyo Women's Medical Coll., Tokyo, Jpn)
Journal Title;Endocr J
Journal Code:F0625A
ISSN:0918-8959
VOL.46;NO.1;PAGE.147-151(1999)
Figure&Table&Reference;FIG.2, TBL.1, REF.21
Pub. Country;Japan
Language;English
Abstract;We report a rare case of acromegaly in which pituitary infarction possibly developed in a GH-producing pituitary adenoma following gastrointestinal bleeding from peptic ulcer. In this case, pituitary infarction resulted in spontaneous remission of acromegaly associated with diabetes mellitus. In addition, detailed histological investigation revealed that clinically silent pituitary apoplexy was mainly an acute ischemic event which occurred recently in a GH-producing adenoma. This event led to massive coagulation necrosis of the tumor and endocrinological improvement. (author abst.)
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