Effect of fluorine substituent on asymmetric reduction of ketones.

Accession number;99A0711824
Title;Effect of fluorine substituent on asymmetric reduction of ketones.
Author; NAKAMURA KAORU (Inst. for Chem. Res., Kyoto Univ.) MATSUDA TOMOKO (Inst. for Chem. Res., Kyoto Univ.)
Journal Title;Fusso Kagaku Toronkai Koen Yoshishu
Journal Code:F0135B
ISSN:
VOL.22nd;NO.;PAGE.26-27(1998)
Figure&Table&Reference;
Pub. Country;Japan
Language;Japanese
Abstract;Effect of fluorine atom on stereoselectivity of reduction of ketones containing fluorine atom by a crude alcohol dehydrogenase from Geotrichum candidum has been investigated. Reduction of trifluoromethyl ketones gives the corresponding alcohols of the opposite configuration to those from methyl ketones. (author abst.)