Inhibitory Effects of Persimmon Leaf Extract on Allergic Reaction in Human Basophilic Leukemia Cells and Mice.

Accession number;99A0562723
Title;Inhibitory Effects of Persimmon Leaf Extract on Allergic Reaction in Human Basophilic Leukemia Cells and Mice.
Author; KOTANI MAYUMI (Sunstar Inc.) FUJITA AKIHITO (Sunstar Inc.) TANAKA TOSHIO (Osaka Univ., Med. Sch.)
Journal Title;Journal of Japanese Society of Nutrition and Food Science
Journal Code:F0624A
ISSN:0287-3516
VOL.52;NO.3;PAGE.147-151(1999)
Figure&Table&Reference;FIG.4, REF.11
Pub. Country;Japan
Language;Japanese
Abstract;The inhibitory effects of persimrnon leaf extract on Type I and Type IV allergic responses were examined. Persimmon leaf extract inhibited the release of histamine from human basophilic leukemia cells (KU812) stimulated with anti-Fc .EPSILON. receptor monoclonal antibody (CRA-1) , the 24-h homologous passive cutaneous anaphylaxis (PCA) reaction in mice, and contact dermatitis induced by 2, 4-dinitrofluorobenzene (DNFB) in mice. These results indicate that persimmon leaf extract possesses an anti-allergic action. (author abst.)
FULLTEXT