Effect of complemental medicine, Ohgi on repair of gastric mucosa lesion.
|
Accession number;99A0448422
|
| Title;Effect of complemental medicine, Ohgi on repair of gastric mucosa lesion. |
| Author;
O SEN'ON
(Juntendo Univ., Sch. of Med.)
O KOEI
(Dosaiigaku)
RIKU FUJI
(Dosaiigaku)
TO KEINEN
(Dosaiigaku)
SHO KIKUKA
(Dosaiigaku)
YO FUYO
(Dosaiigaku)
HIROSE MIYOKO
(Juntendo Univ., Sch. of Med.)
WATANABE SUMIO
(Juntendo Univ., Sch. of Med.)
SATO NOBUHIRO
(Juntendo Univ., Sch. of Med.)
|
Journal Title;Eastern Medicine
|
Journal Code:L0095A
|
ISSN:0911-7768
|
|
VOL.15;NO.1;PAGE.33-37(1999)
|
| Figure&Table&Reference;FIG.2, REF.11 |
| Pub. Country;Japan |
| Language;Japanese |
| Abstract;The surface layer of the gastric mucosa is susceptible to injury, because it is constantly irritated by intrinsic and extrinsic aggressive factors, such as Helicobacter pyroli, gastric acid, digestive enzymes, bile, alcohol, and drugs. At the same time, however, it has a high repair potential owing to the activities of protective factors such as mucus and prostaglandins, and to the activities of blood flow and proliferative factors. Under normal circumstances, cell turnover in the gastric surface layer is rather rapid and in humans the cells are usually replaced in a 4- to -5 day cycle to maintain homeostasis. In peptic ulcer disease, repair potential controls the speed of improvement. Intractable ulcer means a lesion state in which ulcer repair is difficult, and under the circumstances, it is cosidered that aggressive factors(jaki:xie qi) predominate over protective factors(seiki:zhen qi). Invigoration therapy(ho-ho:bu fa) in Chinese medicine is well known to be quite effective in the treatment of infirm patients with intractable diseases. Ohgi(Huang qi) and Yakuyo ninjin(Renshen) are representative of Hoki zai(Bu qi ji), although the details of the true nature and mechanism of Hoki(Bu qi) have not yet been determined. We reported that injection of Jin baku(Shen mai), whose main component is Ninjin, has a promoting action on the repair of gastric mucosal leions. In the present study, we established a lesion model using primary culture cells of the rabbit gastric mucosal surface layer, and observed the effects of injection of Ohgi on lesion repair. (author abst.) |
|
|
|
Related Articles;
|
|
