The Role of Angioscopy and Intravascular Ultrasound Imaging in Acute Coronary Syndrome.

Accession number;99A0480428
Title;The Role of Angioscopy and Intravascular Ultrasound Imaging in Acute Coronary Syndrome.
Author; NOMURA MASANORI (Fujita Health Univ., Sch. of Med.) KUROKAWA HIROSHI (Fujita Health Univ., Sch. of Med.) ISHII JUN'ICHI (Fujita Health Univ., Sch. of Med.) ANDO TOSHIKAZU (Fujita Health Univ., Sch. of Med.) ITO MIKIYA (Fujita Health Univ., Sch. of Med.) TAGA SHIN (Fujita Health Univ., Sch. of Med.) MORI YOSHIHISA (Fujita Health Univ., Sch. of Med.) NARUSE HIROYUKI (Fujita Health Univ., Sch. of Med.) HISHIDA HITOSHI (Fujita Health Univ., Sch. of Med.)
Journal Title;J Cardiol
Journal Code:Y0264A
ISSN:0914-5087
VOL.33;NO.Supplement 1;PAGE.17-21(1999)
Figure&Table&Reference;FIG.4, REF.12
Pub. Country;Japan
Language;Japanese
Abstract;Evaluation of the severity of coronary atherosclerosis by intracoronary imaging may be closely relevant with the prevention and treatment of acute coronary syndromes. Coronary angioscopy as one of the innovative methods of imaging and intravascular ultrasound makes the insight visualization of coronary vessel wall and histological recognition possible recently. Yellow plaques rich in lipid materials and covered by thin membrane are more often ruptured than white ones to cause acute coronary syndromes. In patients with unstable angina and acute myocardial infarction, the yellow plaques with intimal flaps and irregularities are frequently observed by angioscopy. Angioscopy is also the most powerful tool to detect intracoronary thrombus. In patients with acute myocardial infarction, thrombosis occludes vessel lumen totally, but it does not in the nustable angina cases. After thrombolytic therapy, the white thrombus is more often observed than the red one. Although angioscopy is superior to any other examination in diagnosing thrombosis, some complicated plaques are difficult to distinguish from thrombus. In addition to measurements of vascular dimension and plaque volume, histological diagnosis of plaque is being made by intravascular ultrasound. More precise evaluation of plaque histology may be a clue to predict the occurrence of acute coronary syndrome. Intravascular ultrasound is not so useful enough to diagnose thrombosis. In conclusion, the applications of intravascular imaging technologies, such as angioscopy and intravascular ultrasound, may play a critical role in the diagnosis and treatment of acute coronary syndromes. (author abst.)