|
Accession number;00A0163506
|
| Title;Photo-controllable complexation behavior of artificial trihydroxamate siderophores containing an azobenzene framework with ferric ion. |
| Author;
MASUDA TAKESHI
(Osaka City Univ., Fac. of Eng.)
ASARI SAYAKA
(Osaka City Univ., Fac. of Eng.)
IZUMI TOSHIYUKI
(Osaka City Univ., Fac. of Eng.)
NAGASAKI TAKESHI
(Osaka City Univ., Fac. of Eng.)
TAMAGAKI SEIZO
(Osaka City Univ., Fac. of Eng.)
|
Journal Title;Abstracts. Symposium on Biofunctional Chemistry
|
Journal Code:L0836A
|
ISSN:
|
|
VOL.14th;NO.;PAGE.96-97(1999)
|
| Figure&Table&Reference; |
| Pub. Country;Japan |
| Language;Japanese |
| Abstract;A variety of microorganisms produce low-molecular-weight iron carrier molecules called siderophores, which solubilize iron and make it available to iron-deficient cells. In this study a novel photo-responsive trihydroxamate siderophore containing an azobenzene framework was synthesized. First of all, we estimated photo-control of complexation behavior of the artificial siderophore with ferric ion utilizing the cis-trans isomerization of the azobenzene moiety, then controlled the bacterial growth by regulating the siderophore-mediated iron uptake depending on structure of the complex. Microbial iron transport studies using the photo-responsive iron uptake system in Aureobacterium flavescens JG-9 was investigated. While cis-Azo-Gly3 can promote the growth of this siderophore-requiring strain comparable to natural siderohore desferrioxamine B, trans-Azo-Gly3 dose not affect the bacterial growth as compared with the growth assay in the absence of siderophore (Figure 3). (author abst.) |
|
|
|
Related Articles;
|
