Comparison of Primary and Secondary Sjoegren's Syndrome.

Accession number;00A0262558
Title;Comparison of Primary and Secondary Sjoegren's Syndrome.
Author; NAKAMURA YO (Kyoto Prefect. Univ. of Med.) YOKOI NORIHIKO (Kyoto Prefect. Univ. of Med.) INATOMI TSUTOMU (Kyoto Prefect. Univ. of Med.) TAKADA YOKO (Kyoto Prefect. Univ. of Med.) KOMURO AOI (Kyoto Prefect. Univ. of Med.) SUGITA JIRO (Kyoto Prefect. Univ. of Med.) KINOSHITA SHIGERU (Kyoto Prefect. Univ. of Med.)
Journal Title;Journal of Japanese Ophthalmological Society
Journal Code:Z0666A
ISSN:0029-0203
VOL.104;NO.2;PAGE.110-113(2000)
Figure&Table&Reference;FIG.2, TBL.1, REF.19
Pub. Country;Japan
Language;Japanese
Abstract;Purpose: We studied the difference in severity between primary and secondary Sjoegren's syndrome (SS). Subjects and Methods: Two groups of patients (all females, mean age:58 years), 31 with primary SS and 18 with secondary SS were studied. We performed the following dry eye tests:fluorescein score and Rose Bengal staining, grading of tear lipid layer interference patterns, measurement of fluorescein break up time, cotton thread test, and Schirmer-1 test. Auto antibodies were also investigated. Results: There was no siguificant difference between primary and secondary SS with respect to any dry eye tests or auto antibodies. In primary SS, however, the presence of anti SS-A antibody was significantly correlated with Rose Bengal scores (p=0.044). Conclusion: The severity of SS is independent of the primary or secondary type . In primary SS, the presense of anti SS-A antibody may be correlated with the severity. (author abst.)
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