The Role of Paraxial Protocadherin in Morphogenetic Cell Movement during Gastrulation.

Accession number;00A0178524
Title;The Role of Paraxial Protocadherin in Morphogenetic Cell Movement during Gastrulation.
Author; YAMAMOTO AKIHITO (Kumamoto Univ. Sch. of Med. Inst. Molecular Embryology and Genetics)
Journal Title;Protein, Nucleic Acid and Enzyme
Journal Code:F0325A
ISSN:0039-9450
VOL.45;NO.2;PAGE.164-169(2000)
Figure&Table&Reference;FIG.5, REF.15
Pub. Country;Japan
Language;Japanese
Abstract;This paper outlines how paraxial protocadherin(PAPC) molecule is involved with gastrulation movement in Xenopus and zebrafish embryos. The functional analysis of PAPC in gastrula of these animals shows that its intermolecular interaction plays important roles in the morphogenetic movements which are divided roughly into three movements, i.e., epiboly, involution, and convergence-extension movements. It strongly indicates that PAPC is the very molecule which controls actual gastrula cell movement on the basis of signals from differentiation controlling factor groups.
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