Imaging and Manipulation of DNA Molecules Using Scanning Tunneling Microscopy.

Accession number;00A0178525
Title;Imaging and Manipulation of DNA Molecules Using Scanning Tunneling Microscopy.
Author; TANAKA HIROYUKI (Inst. of Sci. and Ind. Res., Osaka Univ.) KAWAI TOMOJI (Inst. of Sci. and Ind. Res., Osaka Univ.)
Journal Title;Protein, Nucleic Acid and Enzyme
Journal Code:F0325A
ISSN:0039-9450
VOL.45;NO.2;PAGE.170-175(2000)
Figure&Table&Reference;FIG.8, REF.16
Pub. Country;Japan
Language;Japanese
Abstract;Nucleic acid base molecules, and single and double stranded DNAs are observed by using scanning tunneling microscopy(STM), which images the ruggedness of sample surface by the probe at atomic-scale by constantly retaining tunneling current, and is able to image double helix structure and each base molecule of DNA. This paper introduces first the principle of STM, history of the observation by STM, and major research results on the observation of DNA and molecular operations. It finally describes the future perspectives of DNA researches by STM.
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