Repeated 5-Aminolevulinic Acid-Based Photodynamic Therapy Following Electro-Curettage for Pigmented Basal Cell Carcinoma.
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Accession number;00A0179407
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| Title;Repeated 5-Aminolevulinic Acid-Based Photodynamic Therapy Following Electro-Curettage for Pigmented Basal Cell Carcinoma. |
| Author;
ITOH Y
(National Defense Medical Coll., Tokorozawa, Jpn)
HENTA T
(National Defense Medical Coll., Tokorozawa, Jpn)
NINOMIYA Y
(National Defense Medical Coll., Tokorozawa, Jpn)
TAJIMA S
(National Defense Medical Coll., Tokorozawa, Jpn)
ISHIBASHI A
(National Defense Medical Coll., Tokorozawa, Jpn)
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Journal Title;J Dermatol
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Journal Code:Z0757A
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ISSN:0385-2407
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VOL.27;NO.1;PAGE.10-15(2000)
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| Figure&Table&Reference;FIG.2, TBL.1, REF.20 |
| Pub. Country;Japan |
| Language;English |
| Abstract;5-Aminolevulinic acid-based photodynamic therapy (ALA-PDT) in the standard manner is ineffective for pigmented basal cell carcinoma (pBCC), because melanin absorbs the photoactivating light interred for protoporphyrin IX. The objective of this study was to assess the therapeutic outcome of pBCCs with repeated ALA-PDT following removal of pigmentation with electro-curettage. After electro-curettage, 16 pBCCs Were treated with a combination of topical application of 20% ALA in O/W emulsion and topical instillation of 10% ALA solution, followed by photoactivating light. ALA-PDT was performed more than three times. Fourteen of 16 pBCCs Showed CR. Two pBCCs showing PR or NR were excised. Repeated ALA-PDT following electro-curettage was effective for pBCC. |
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