Binding of Egg-Yolk Low Density Lipoprotein to a Human Monocytic Cell Line UM.

Accession number;00A0371187
Title;Binding of Egg-Yolk Low Density Lipoprotein to a Human Monocytic Cell Line UM.
Author; SUZUKI MICHIKO (Ei・eru・ei) SHINMOTO HIROSHI (Minist. of Agric., For. and Fish., Tohoku Natl. Agric. Exp. Stn.) KOBORI MASUKO (Minist. of Agric., For. and Fish., Natl. Food Res. Inst.) TSUSHIDA TOJIRO (Minist. of Agric., For. and Fish., Natl. Food Res. Inst.) SHINOHARA KAZUKI (Minist. of Agric., For. and Fish., Natl. Food Res. Inst.) YONEKURA MASAMI (Ibaraki Univ., Fac. of Agric.) TSUTSUMI MASAKAZU (Ibaraki Univ., Fac. of Agric.)
Journal Title;Journal of the Japanese Society for Food Science and Technology
Journal Code:F0895A
ISSN:1341-027X
VOL.47;NO.3;PAGE.269-271(2000)
Figure&Table&Reference;FIG.3, TBL.1, REF.11
Pub. Country;Japan
Language;Japanese
Abstract;Egg yolk low density lipoprotein(YLDL) had a growth stimulating activity to a human monocytic cell line UM. Analysis on binding of YLDL labeled with europium(Eu) to the UM cells by time-resolved fluorometory showed that UM cells had a large number of binding sites with low binding affinity on the cell surface. Inhibition analysis of the binding by using human serum lipoproteins suggested the binding site would have an affinity to human very low density lipoprotein. (author abst.)