Effect of Epilepsy Surgery Based on Magnetic Resonance Imaging (MRI) Classification.

Accession number;00A0138283
Title;Effect of Epilepsy Surgery Based on Magnetic Resonance Imaging (MRI) Classification.
Author; FUJII MASAMI (Yamaguchi Univ.) AKIMURA TATSUO (Yamaguchi Univ.) KUBOTA HISASHI (Yamaguchi Univ.) YASUDA HIROAKI (Yamaguchi Univ.) ITO HARUHIDE (Yamaguchi Univ.) HAYASHI TAKASHI (Yamaguchi Univ.) NISHIKAWA MIKI (Yamaguchi Univ.) OGATA HIROKO (Soc. Insur., Shimonoseki Kosei Hosp.)
Journal Title;Neurol Surg
Journal Code:Z0684A
ISSN:0301-2603
VOL.28;NO.1;PAGE.23-29(2000)
Figure&Table&Reference;FIG.1, TBL.2, REF.30
Pub. Country;Japan
Language;Japanese
Abstract;We prospectively analyzed the effect of surgical procedures in epilepsy patients, except for those with mesial temporal lobe epilepsy. Twenty patients with a mean age of 26 years (range 3 to 58 years, 10 male and 10 female) underwent the surgical procedures. These patients were divided into 3 groups according to MRI findings, as follows; group A (localized type) : localized lesions such as angiomas or benign tumors, group B (widespread type) : widespread lesions such as regional encephalitis or stroke, visible on anatomical neuroimaging, and group C (cryptic type) : no lesion visible on anatomical neuroimaging. Following surgery, 11 (85%) of the 13 patients in group A were seizure-free, one showed worthwhile improvement, and one, whose lesion was not removed totally, was unchanged. In group B, two patients (50%) were seizure-free and 2 (50%) showed worthwhile improvement. All the patients in group C showed worthwhile improvement. Lesionectomy, cortical excision, multiple subpial transection (MST) or a combination of these procedures were effective in groups A and B. Patients in group C had a chance to obtain worthwhile improvement by corpus callosotomy or cortical excision. Intracranial EEG recording provides useful information for epilepsy surgery in intractable cases. (author abst.)
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