Acute Infectious Urticaria. Clinical and Laboratory Analysis in Nineteen Patients.

Accession number;00A0259760
Title;Acute Infectious Urticaria. Clinical and Laboratory Analysis in Nineteen Patients.
Author; SAKURAI M (Shizuoka General Hospital, Shizuoka, Jpn) OBA M (Shizuoka General Hospital, Shizuoka, Jpn) MATSUMOTO K (Shizuoka General Hospital, Shizuoka, Jpn) TOKURA Y (Hamamatsu Univ. School Of Medicine, Hamamatsu, Jpn) FURUKAWA F (Hamamatsu Univ. School Of Medicine, Hamamatsu, Jpn) TAKIGAWA M (Hamamatsu Univ. School Of Medicine, Hamamatsu, Jpn)
Journal Title;J Dermatol
Journal Code:Z0757A
ISSN:0385-2407
VOL.27;NO.2;PAGE.87-93(2000)
Figure&Table&Reference;FIG.3, TBL.2, REF.17
Pub. Country;Japan
Language;English
Abstract;We treated 19 Japanese patients with acute urticaria presumably caused by infection during the five years from 1994 to 1998. The patients' ages ranged from 2 to 66 years (8 males and 11 females). Most of them had urticaria, angioedema, high fever, neutrophilia, and high serum levels of C reactive protein (CRP). The skin rash lasted more than 24 hours. In four patients, a flow cytometric analysis revealed that the percentage of circulating T cells bearing T-cell receptor V.BETA.3 was decreased during the active stage and that this decrease was susiained for at least 2 to 3 weeks. This suggests that certain T-cell populations were numerically altered in association with the occurrence of the disease. A retrospective review indicated that the combination therapy with corticosteroid and antibiotics was more effective than the single use of either agent.
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