Optic Disc Blood Flow Measured by Scanning Laser-Doppler Flowmetry Using a New Analysis Program.

Accession number;00A0359867
Title;Optic Disc Blood Flow Measured by Scanning Laser-Doppler Flowmetry Using a New Analysis Program.
Author; HAYASHI NOBUHITO (Jieitai Cent. Hosp.) TOMITA GOJI (Gifu Univ., Sch. of Med.) KITAZAWA YOSHIAKI (Gifu Univ., Sch. of Med.)
Journal Title;Journal of Japanese Ophthalmological Society
Journal Code:Z0666A
ISSN:0029-0203
VOL.104;NO.3;PAGE.148-153(2000)
Figure&Table&Reference;FIG.5, TBL.3, REF.10
Pub. Country;Japan
Language;Japanese
Abstract;Purpose: Using a new analysis program for scanning laser-Doppler flowmetry (SLDF) by a Heidelberg retina flowmeter (HRF), we studied the relation between flow and visual field or disc morphology. Subjects and Methods: In 42 eyes of 21 patients with normal tension glaucoma (NTG) the mean-flow of the HRF blood flow parameters at the disc rim was measured and analyzed by a new analysis program for perfusion maps (the SLDF analysis tool), to minimize the influence of large vessels or/and artifacts caused by small eye movements. We investigated whether difference of the mean-flow between a pair of eyes had any relation to differences between a pair of eyes in visual field indices and those in disc morphological measurements of the Heidelberg retina tomograph. Results: We found statistically significant correlations between the mean-flow and optic disc parameters (Disk Area, Cup Area, Height Variation Contour, Cup Volume, Rim Volume, Mean RNFL Thickness). We found no statistically significant correlations between the mean-flow and visual field parameters (mean deviation, corrected pattern standard deviation). Conclusion: The results suggested that eyes with less flow in the optic disc rim have more advanced glaucomatous morphological changes. (author abst.)
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