Anti-allergenic Properties of the Fruiting Bodies of Sarcodon aspratus.

Accession number;00A0464798
Title;Anti-allergenic Properties of the Fruiting Bodies of Sarcodon aspratus.
Author; TATEISHI KOICHI (Shinshu Univ., Fac. of Agric.) HOSONO TAKUYA (Shinshu Univ., Fac. of Agric.) SHIMAZU SEIICHIRO (Fujimoto Pharm. Co., Ltd.) FUJIMOTO MICHITARO (Fujimoto Pharm. Co., Ltd.)
Journal Title;Journal of the Japanese Society for Food Science and Technology
Journal Code:F0895A
ISSN:1341-027X
VOL.47;NO.4;PAGE.281-286(2000)
Figure&Table&Reference;FIG.3, TBL.2, REF.23
Pub. Country;Japan
Language;Japanese
Abstract;The anti-allergenic properties of the fruiting bodies of Sarcodon aspratus(Berk) Ito were elucidated by the inhibition of the heterologous passive cutaneous anaphylaxis(PCA) against guinea pig. The active fraction was purified as the single peak by HPLC-gelfiltration, after the hot water extraction of the dried fruiting bodies, and successive dialysis, precipitation by ethanol and DEAE-cellulose column chromatography of the precipitates. The purified active fraction was of the molecular weight 1,300,000, and the main composition was the sugar and protein, containing arabinose, xylose, glucose, galactose, and mannose as sugars, and 20 kinds of amino acids. This active fraction inhibited the formation of the blue spots caused by PCA, when it(1mg/ml) was injected with the rabbit anti-bovine .BETA.-lactoglobulin anti serum. (author abst.)