|
Accession number;00A0204404
|
| Title;Molecular Mechanisms of the Pathway Formation in the Fetal Rat Cerebral Neocortex. |
| Author;
KAWANO HITOSHI
(Tokyo Metrop. Inst. for Neurosci.)
KAWAMURA KOKI
(Sch. of Med., Keio Univ.)
|
Journal Title;Protein, Nucleic Acid and Enzyme
|
Journal Code:F0325A
|
ISSN:0039-9450
|
|
VOL.45;NO.3;PAGE.279-285(2000)
|
| Figure&Table&Reference;FIG.7, REF.29 |
| Pub. Country;Japan |
| Language;Japanese |
| Abstract;The thalamus cortical fascicle projected to the cerebral neocortex from the thalamus has been clarified. In the thalamus cortical fascicle formation in the neocortical rudiment, the heteromolecular interaction between the nerve cell adhesion molecule and proteoglycan has been suppossed to be important. Such a possibility is also supported from the analysis of the reeler mouse with an abnormal neocortex layer formation. And, in the micropthalmia rat deficient in the transcription controlling factor Pax-6, walking abnormality of the thalamus cortical fascicle was observed in the diencephalon lebels, Pax 6 proved to carry out an important work for the initial route formation of the thalamus cortical fascicle. These mutant animals are models suitable to investigation of the molecular mechanism of thalamus cortical fascicle formation. |
|
|
|
Related Articles;
|
|
