The Cadherin Gene Family that Regulate Neural Circuits Formation and Higher Order Brain Functions.
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Accession number;00A0204407
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| Title;The Cadherin Gene Family that Regulate Neural Circuits Formation and Higher Order Brain Functions. |
| Author;
CHISAKA OSAMU
(Kyoto Univ., Grad. Sch.)
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Journal Title;Protein, Nucleic Acid and Enzyme
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Journal Code:F0325A
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ISSN:0039-9450
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VOL.45;NO.3;PAGE.301-306(2000)
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| Figure&Table&Reference;FIG.4, REF.22 |
| Pub. Country;Japan |
| Language;Japanese |
| Abstract;The cell adhesion molecule cadherin exists in the multicellular organisms without asking the vertebrate and invertebrate, and plays an important role in the tissue construction. Recently, a cadherin group showing a specific manifestation pattern in the nervous system has been found, it has been clarified that the cadherin has an important action for the neuronal circuit formation and synaptic transmission, from the analysis of Drophila mutant and the mouse target gene destrucion body. Regarding the cadherin superfamily, the authors summarized its composition, involvement to the nervous system manifestation, axon elongation and bundling, function on the target recognition, involvement to the synapse plasticity and higher brain function etc.. |
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