Morphogenesis of the Optic Tectum and Retinotectal Map Formation.
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Accession number;00A0204409
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| Title;Morphogenesis of the Optic Tectum and Retinotectal Map Formation. |
| Author;
NAKAMURA HARUKAZU
(Res. Inst. Tuberculosis and Cancer, Tohoku Univ.)
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Journal Title;Protein, Nucleic Acid and Enzyme
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Journal Code:F0325A
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ISSN:0039-9450
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VOL.45;NO.3;PAGE.316-322,211(2000)
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| Figure&Table&Reference;FIG.7, REF.29 |
| Pub. Country;Japan |
| Language;Japanese |
| Abstract;From the retina, it is projected onto the optic tectum which is the center of visual sense, in the 2-dimensionally and in the strictly corresponded relation. Therefore, each of the retina and the optic tectum is formed as a compartment, a location specificity develops within the compartment with the result to cause an appearance of a molecule related to the target selection. In the present report, the authors explained the fact that an interaction between Pax-2,5 and Fgf 8 fulfils an important role, in its downstream, En participates in the location specificity formation along the optic tectum longitudinal axis and molecules of Ephrin-A 2, A 5 etc. related in the target selection appear through the induction by En. |
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