"Adenoid" Glioblastoma.

Accession number;00A0387857
Title;"Adenoid" Glioblastoma.
Author; SHINTAKU MASAYUKI (Osaka Red Cross Hosp.) NAKATSU SHOJI (Osaka Red Cross Hosp.) OKAMOTO SHIN'ICHIRO (Osaka Red Cross Hosp.)
Journal Title;Neurol Surg
Journal Code:Z0684A
ISSN:0301-2603
VOL.28;NO.4;PAGE.359-365(2000)
Figure&Table&Reference;FIG.6, REF.21
Pub. Country;Japan
Language;Japanese
Abstract;A surgrcal case of glioblastoma which showed a pronounced "adenoid" (or "epithelioid") appearance was reported. The patient was an 81-year-old woman, who presented with unsteady gait. Neuroradiological examination revealed three discrete mass lesions located in the 1-frontal, 1-parieto-occipital, and r-occipito-temporal lobes. Despite the subtotal removal of two of the three lesions and postoperative chemotherapy and radiotherapy, the patient died 21 months after the onset of illness. Histopathological examination of the resected tumors revealed typical features of glioblastoma in the peripheral region of the tumor. In the central region, the tumor cells were arranged in a papillary fashion or formed solid, sheet-like cell nests and were surrounded by fibrous connective tissue septa. Although the histopathological appearance of the tumor closely resembled metastasis of adenocarcinoma, the imnrunohistochemical and ultrastructural studies of the tumor failed to detect evidence of a definite differentiation towards epithelial cells. (author abst.)
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