Tetracycline resistant and polymyxin B sensitive vibrio cholerae O1 E1 tor isolated from the recent epidemics.

Accession number;00A0479784
Title;Tetracycline resistant and polymyxin B sensitive vibrio cholerae O1 E1 tor isolated from the recent epidemics.
Author; IWANAGA M (Univ. Ryukyus, Okinawa, Jpn) INSISIENGMAY S (Center For Lab. And Epidemiology, Vientiane, Lao) HIGA N (Univ. Ryukyus, Okinawa, Jpn) SISAVATH L (Center For Lab. And Epidemiology, Vientiane, Lao)
Journal Title;Japanese Journal of Tropical Medicine and Hygiene
Journal Code:Z0546A
ISSN:0304-2146
VOL.28;NO.1;PAGE.15-18(2000)
Figure&Table&Reference;TBL.3, REF.16
Pub. Country;Japan
Language;English
Abstract;By examining 99 Vibrio cholerae O1 isolates from cholera epidemics in a variety of areas in Laos in 1998, we found two unusual characteristics of the organisms. All except 4 isolates were moderately resistant to tetracycline without having plasmids, and susceptibilities to the other drugs were as expected. Eleven isolates showed the same level of susceptibility to polymyxin B as classical V. cholerae O1. With the exception of 4 tetracycline-susceptible strains, all the isolates were resistant to or poorly sensitive to the vibriostatic agent O/129 (2,4-diamino-6,7-di-iso-propyl pteridine phosphate). All isolates, including those susceptible to polymyxin B, produced E1 Tor hemolysin which was neutralized by anti-E1 Tor hemolysin and were resistant to cholera phage IV, indicating that they were of the E1 Tor biotype. (author abst.)