Clinical Application of Autoactivation PET Imaging Derived form C-12 Ion Radiotherapy.

Accession number;99A1042718
Title;Clinical Application of Autoactivation PET Imaging Derived form C-12 Ion Radiotherapy.
Author; YOSHIKAWA KYOSAN (National Inst. of Radiological Sciences)
Journal Title;NIRS-M (Natl Inst Radiol Sci)
Journal Code:Z0881A
ISSN:
VOL.;NO.132;PAGE.74-80(1999)
Figure&Table&Reference;FIG.13, TBL.1
Pub. Country;Japan
Language;Japanese
Abstract;Clinical application of PET imaging of autoactivation derived from C-12 ion radiotherapy was studied. Quality of the image of autoactivation in each region from the brain to lower pelvis was checked. Images were fairly good in all regions. There was a strong RI distribution at the beam entrance area compared to deep areas from the body surface. Bone showed especially strong RI activity. We think that is because bone has very low blood flow. The RI derived form C-12 ion radiotherapy is washed out from regions with high blood flow, So, regional blood flow affects the quality of the autoactivation PET image. We got fine PET images for brain cancer, lung cancer, esophageal cancer and liver cancer. There was an RI distribution at the vertebra which is on the opposite side from the beam entrance point in the case of lung cancer. The RI was distributed in a wide area in the case of uterine cervical cancer, but no RI activity in the cervical tumor was detected due to the high regional blood flow for the uterine cervical cancer. We found that regional metabolism such as blood flow of the tumor was very important factor which affects the autoactivation PET image quality. There might be some possibility that a high RI distribution in the tumor means low metabolism of the tumor. The activity of RI derived from autoactivation might correlate with the level of damage of the tumor by C-12 ion radiotherapy. (author abst.)