Science Links Japan | Antimicrobial susceptibility of organisms isolated from patients with complicated urinary tract infections during 1997 and 1998.

Antimicrobial susceptibility of organisms isolated from patients with complicated urinary tract infections during 1997 and 1998.

Accession number;00A0471424

Title;Antimicrobial susceptibility of organisms isolated from patients with complicated urinary tract infections during 1997 and 1998.

Author; HAYAMI HIROSHI (Kagoshima Univ., Fac. of Med.) KAWAHARA MOTOSHI (Kagoshima Univ., Fac. of Med.) KITAGAWA TOSHIHIRO (Kagoshima Univ., Fac. of Med.) ETA SHIN'ICHI (Kagoshima Univ., Fac. of Med.) TOKIWA MITSUHIRO (Kagoshima Univ., Fac. of Med.) GOTO TOSHIHIRO (Kagoshima Univ., Fac. of Med.)

Journal Title;Japanese Journal of Chemotherapy

Journal Code:F0608A

ISSN:1340-7007

VOL.48;NO.4;PAGE.278-284(2000)

Figure&Table&Reference;FIG.4, TBL.7, REF.15

Pub. Country;Japan

Language;Japanese

Abstract;Using the agar dilution method, susceptibilities to various antimicrobial agents were examined for methicillin-resistant Staphylococcus aureus (MRSA), Enterococcus faecalis, Escherichia coli and Pseudomonas aeruginosa that had been isolated from patients with complicated urinary tract infections (UTIs) in the Department of Urology, Kagoshima University, from January 1997 through December 1998, at an inoculum size of 106CFU/mL. Vancomycin showed the most potent antibacterial activity against MRSA and E. faecalis, with MIC90 of 0.78 and 3.13 .MU.g/mL, respectively. Carbapenems showed potent antibacterial activity against E. faecalis, with an MIC90 of less than 12.5 .MU.g/mL. Carbapenems and most of the cephems showed potent antibacterial activity against E. coli, that of meropenem (MEPM) being especially high with an MIC90 of less than 0.025 .MU.g/mL. Tobramycin showed the most potent antibacterial activity against P. aeruginosa, with an MIC90 of 1.56 .MU.g/mL. On regression analysis, positive correlations were observed between MICs of MEPM and imipenem (IPM), MEPM and panipenem (PAPM), and IPM and PAPM against tested strains, with correlation coefficients ranging between 0.602 and 0.966. (author abst.)

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