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A study on the optimized fractionation and clinical evaluation of radiation response in carbon ion therapy for hepatocellular carcinoma.

Accession number;00A0557797

Title;A study on the optimized fractionation and clinical evaluation of radiation response in carbon ion therapy for hepatocellular carcinoma.

Author; KATO HIROTOSHI (National Inst. of Radiological Sciences) TSUJII HIROHIKO (National Inst. of Radiological Sciences) MIZOE JUN'ETSU (National Inst. of Radiological Sciences) MATSUOKA YOSHISUKE (National Inst. of Radiological Sciences) KANDATSU SUSUMU (National Inst. of Radiological Sciences) YOSHIKAWA KYOSAN (National Inst. of Radiological Sciences) KOGA MASAHISA (National Inst. of Radiological Sciences) FUJITA JUN'ICHI (National Inst. of Radiological Sciences) OTO MASAO (National Inst. of Radiological Sciences)

Journal Title;NIRS-M (Natl Inst Radiol Sci)

Journal Code:Z0881A

ISSN:

VOL.;NO.133;PAGE.24-26(1999)

Figure&Table&Reference;TBL.1

Pub. Country;Japan

Language;Japanese

Abstract;A total of 34 patients with hepatocellular carcinoma (HCC) associated with liver cirrhosis were treated by carbon ion beams with graded doses ranging from 48.0 to 69.6 GyE according to a protocol of hypofractionated irradiation (4-12frs). In this report, it is preliminary suggested that this irradiation regimen of carbon ions appeared to be well tolerated as compared to the carbon ion therapy with 15 fractions used in the first clinical trial while anti-cancer effects seemed to be similar in both irradiation methods. (author abst.)

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