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Accession number;00A0593239
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| Title;Antimicrobial susceptibility of clinically isolated strains of Haemophilus influenzae. |
| Author;
WATANABE SHINSUKE
(Kawasaki Med. Sch.)
NIKI YOSHITO
(Kawasaki Med. Sch.)
TAMADA SADAO
(Kawasaki Med. Sch.)
KAWABATA SATOSHI
(Kawasaki Med. Sch.)
YOSHIDA KOICHIRO
(Kawasaki Med. Sch.)
MIYASHITA NAOYUKI
(Kawasaki Med. Sch.)
NAKAJIMA MASAMITSU
(Kawasaki Med. Sch.)
MATSUSHIMA TOSHIHARU
(Kawasaki Med. Sch.)
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Journal Title;Japanese Journal of Chemotherapy
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Journal Code:F0608A
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ISSN:1340-7007
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VOL.48;NO.5;PAGE.333-340(2000)
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| Figure&Table&Reference;TBL.8, REF.23 |
| Pub. Country;Japan |
| Language;Japanese |
| Abstract;We investigated the characteristics of 178 strains of Haemophilus influenzae clinically isolated between January 1996 and April 1998, with respect to .BETA.-lactamase production, serotype, and antimicrobial susceptibility. Of these, 4.5% were type-b strains and 87.6% were not typeable. Overall, 13.5% of the isolates produced .BETA.-lactamase. Of the 154 .BETA.-lactamase-negative H. influenzae, 4 strains (2.6%) were resistant to ampicillin (.BETA.-lactamase-negative ampicillin-resistant; BLNAR). Two strains (8.3%) of the 24 .BETA.-lactamase-positive H. influenzae were resistant to amoxicillin/clavulanate (.BETA.-lactamase-positive amoxicillin/clavulanate-resistant; BLPACR). The percentages of all tested isolates composed of BLNAR and BLPACR strains were 2.2% and 1.1%, respectively. Overall, 3.9% of the isolates were resistant to ciprofloxacin and levofloxacin. The clinical courses of the patients infected with these resistant strains were good, and no treatment failure have been found. (author abst.) |
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