A study of 57 cases with enterocolitis after gastrointestinal surgery: effect of antibiotics used before and after surgery.
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Accession number;00A0593241
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| Title;A study of 57 cases with enterocolitis after gastrointestinal surgery: effect of antibiotics used before and after surgery. |
| Author;
HANATANI YUJI
(Teikyo Univ.)
KODAIRA SUSUMU
(Teikyo Univ.)
ASAGOE TATSUO
(Teikyo Univ.)
GIBO JUN'ICHI
(Teikyo Univ.)
TOEDA HIROYUKI
(Teikyo Univ.)
KAWAKAMI SAYOKO
(Teikyo Univ.)
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Journal Title;Japanese Journal of Chemotherapy
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Journal Code:F0608A
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ISSN:1340-7007
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VOL.48;NO.5;PAGE.347-352(2000)
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| Figure&Table&Reference;TBL.9, REF.19 |
| Pub. Country;Japan |
| Language;Japanese |
| Abstract;We examined 1,155 patients who underwent gastrointestinal surgery during 6 years, to ascertain the incidence and background factors of postoperative enterocolitis and MRSA enterocolitis. Postoperative patients who had more than 4 episodes of diarrhea per day with no evident cause for 2 or more consecutive days were diagnosed as having postoperative enterocolitis. MRSA enterocolitis was diagnosed when MRSA was isolated from the stool of the patients with postoperative enterocolitis. We experienced 57 postoperative enterocolitis cases, i.e. the incidences of postoperative enterocolitis were 4.9% of 1,155 patients and 10.3% of 555 postoperative infections. MRSA were isolated from 28 (60.9%) out of 48 postoperative enterocolitis cases who underwent bacteriological examination. The incidence of MRSA enterocolitis was significantly higher in contaminated operations (P<0.01) and men (P<0.05). There was no significant difference in the incidence of MRSA enterocolitis according to the site of operation, age of patients, malignant versus benign of the disease, and with or without concomitant disease. Postoperative enterocolitis occurred frequently for 4-10 postoperative days, and there was no significant difference in the time of outbreak according to with or without isolation of MRSA. There was no significant difference in the incidence of postoperative enterocolitis and MRSA enterocolitis according to with or without administration of antibiotics preoperatively. The incidence of postoperative enterocolitis (P<0.05, P<0.001) and MRSA enterocolitis (P<0.01, P<0.001) in the patients who were administered oxacephems or third-generation cephems, and carbapenems after surgery were significantly higher than those in the patients who were administered first- or second-generation cephems after surgery.... (author abst.) |
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