A Case of Hirsutism, Hypomenorrhea and Obese Type Diabetes Improved by Troglitazone.
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Accession number;00A0560446
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| Title;A Case of Hirsutism, Hypomenorrhea and Obese Type Diabetes Improved by Troglitazone. |
| Author;
KOYAMA KAZUNORI
(National Tokyo Medical Center, JPN)
SAITO YASUHIRO
(National Tokyo Medical Center, JPN)
AOKI MAKOTO
(National Tokyo Medical Center, JPN)
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Journal Title;Japanese Journal of National Medical Services
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Journal Code:F0707A
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ISSN:0021-1699
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VOL.54;NO.5;PAGE.235-238(2000)
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| Figure&Table&Reference;FIG.2, TBL.1, REF.9 |
| Pub. Country;Japan |
| Language;Japanese |
| Abstract;A 18 year-old adolescent girl with obese type diabetes and hypomenorrhea was admitted to our hospital. She was hirsute due to ovarian hyperandrogenesis, caused by hyperinsulinemia via insulin resistance. No abnormal findings were detected by CT scan or echography in her ovarian and adrenal glands. She was not diagnosed as polycystic ovary syndrome (PCOS). However, her metabolic and endocrine features are identical to those seen in adult woman with PCOS. A new insulin-sensitizing agent, troglitazone, improved insulin action, ameliorated glucose intolerance and also decreased insulin and androgen levels. Troglitazone is a novel useful drug for PCOS-like adolescent female. (author abst.) |
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