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Accession number;00A0470792
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| Title;Two Cases of Methicillin-resistant Staphylococcus aureus (MRSA) Sepsis Following Craniotomy. |
| Author;
KASUYA HIDETOSHI
(Tokyo Women's Med. Coll.)
KIKUCHI KEN
(Tokyo Women's Med. Coll.)
IMAMURA TSUYOSHI
(Tokyo Women's Med. Coll.)
KAWASHIMA AKITSUGU
(Tokyo Women's Med. Coll.)
AIHARA YASUO
(Tokyo Women's Med. Coll.)
OCHIAI TAKU
(Tokyo Women's Med. Coll.)
YAMAGUCHI KOJI
(Tokyo Women's Med. Coll.)
FUKAMACHI KIKUYO
(Tokyo Women's Med. Coll.)
TOZUKA KYOICHI
(Tokyo Women's Med. Coll.)
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Journal Title;Neurol Surg
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Journal Code:Z0684A
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ISSN:0301-2603
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VOL.28;NO.5;PAGE.429-434(2000)
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| Figure&Table&Reference;FIG.6, REF.23 |
| Pub. Country;Japan |
| Language;Japanese |
| Abstract;We report here two cases of MRSA sepsis following craniotomy. In case 1, a petroclival meningioma was subtotally removed and lumbar drainage was inserted postoperatively to prevent cerebrospinal fluid leakage. Ventriculo-peritoneal shunt was performed after meningitis was treated with vancomycin and panipenem/betamipron. Two weeks after the procedure, the patient revealed continuous spiking fevers related to MRSA sepsis, which did not improve with vancomycin and arbekacin administration. The focus of infection was found by scintigraphy and CT by 67Ga to be spondylo-diskitis at the level of L2-L3. The lesion was removed and bone from the iliac crest grafted. In case 2, seven days after suirgery for multiple meningioma, the patient exhibited spiking fevers and swelling in the left leg. The central venous catheter was removed from the left femoral vein and MRSA was found from blood culture. The patient was treate,d with arbekacin (200mg/day) . Venous thrombosis diagnosed by CT was treated with heparin. Symptoms related to the infection and laboratory data did not improve because the concentration of arbekacin in the blood did not reach an effective level. The symptoms markedly improved when the dose of arbekacin was doubled (400mg/day). (author abst.) |
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