The Influence of Age and Gender on Serum Soluble Interleukin-2 Receptor (sIL-2 R) and Intercellular Adhesion Molecule-1 (sICAM-1) Levels.

Accession number;00A0534633
Title;The Influence of Age and Gender on Serum Soluble Interleukin-2 Receptor (sIL-2 R) and Intercellular Adhesion Molecule-1 (sICAM-1) Levels.
Author; IHARA AKIHIRO (Kure National Hospital) KATAYAMA SHOICHI (Kure National Hospital)
Journal Title;Japanese Journal of National Medical Services
Journal Code:F0707A
ISSN:0021-1699
VOL.54;NO.4;PAGE.167-171(2000)
Figure&Table&Reference;FIG.5, REF.25
Pub. Country;Japan
Language;Japanese
Abstract;We examed soluble interleukin-2 receptor (slL-2 R) and soluble intercellular adhesion molecule-l (sICAM-1) in venous blood from healthy subjects. slL-2 R and sICAM-1 are correlated with age (r=0.207, n=174, p=0.0064 and r=0.248, n=126, p=0.0065, respectively). Both factors had significantly higher levels in males than in females (p<0.007). There was statistically significant correlation between sIL-2R and sICAM-1. Changes in serum slL-2 R and sICAM-1 levels with aging and increased levels in men may be related to the developement of atherosclerosis. (author abst.)