A Case of Nodular Cutaneous Lupus Mucinosis.
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Accession number;00A0754261
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| Title;A Case of Nodular Cutaneous Lupus Mucinosis. |
| Author;
MURAKAMI KAORI
(Showa Univ., Sch. of Med.)
SUZUKI HIROTAKE
(Showa Univ., Sch. of Med.)
KUDO RIKA
(Showa Univ., Sch. of Med.)
SO INKETSU
(Showa Univ., Sch. of Med.)
SUEKI HIROHIKO
(Showa Univ., Sch. of Med.)
IIJIMA MASAFUMI
(Showa Univ., Sch. of Med.)
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Journal Title;Skin Research
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Journal Code:Z0014B
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ISSN:0018-1390
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VOL.42;NO.2;PAGE.167-174(2000)
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| Figure&Table&Reference;FIG.7, TBL.2, REF.34 |
| Pub. Country;Japan |
| Language;Japanese |
| Abstract;A 32-year-old man was admitted to the Department of Internal Medicine because of 6-month history of the facial edema. The examination and laboratory data suggested SLE, however the final diagnosis had not been done. Three months later, he developed erythematous plaques on the face, trunk and upper limbs. The plaques on the back have been gradually elevated. Physical examination revealed multiple, finger-head sized, darkly reddish nodules over the back, malar rash and discoid rash on the palms and fingers. Histologically, the nodular lesions revealed large amounts of mucin stained with alcian blue between collagen bundles and perivascular and periadnexal infiltration of lymphocytes. Lupus band test of the discoid rash was positive, whereas that of normal skin was negative. The titer of serum ANF and anti-ds-DNA antibody was elevated with hypocomplementemia. No nephropathy was observed. The diagnosis of NCLM associated with SLE was made, and 24mg/day of methylprednisolone was administrated and then it was tapered. Topical corticosteroid was effective, but the lesions of NCLM could not be prevented, irrelevant to the activity of SLE. (author abst.) |
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