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Accession number;00A0754262
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| Title;A Case of Vitiligo with Inflammatory Raised Borders. |
| Author;
HAYAMI JUNJI
(Kansai Med. Univ.)
YAMAWAKI MITSUO
(Kansai Med. Univ.)
HORIO TAKESHI
(Kansai Med. Univ.)
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Journal Title;Skin Research
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Journal Code:Z0014B
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ISSN:0018-1390
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VOL.42;NO.2;PAGE.175-178(2000)
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| Figure&Table&Reference;FIG.2, REF.16 |
| Pub. Country;Japan |
| Language;Japanese |
| Abstract;The pathogenesis of vitiligo is still unknown, although there are some evidences that cellular immunity may be involved. A 61-year-old Japanese male had developed depigmented macule surrounded by annular erythema on the cervical region, which had gradually progressed. Ill-defined, irregularly shaped erythema was seen on the periphery of the depigmented lesions. The clinical diagnosis of vitiligo with inflammatory raised borders was made. A skin biopsy from an erythematous lesion revealed spongiosis and vacuolar alteration of the basal layer and moderate dermal lymphocytic infiltration. At the depigmented lesion, loss of melanocytes and scant lymphocytes could be detected. The patient was treated successfully by oral steroid(betamethasone, d-chlorpheniramine maleate) and topical steroid(0.05% fluocinonide cream) administration. The early treatment of this disorder for the inflammation seems to be important to prevent vitiligo progression. (author abst.) |
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