Study on penetration of oral antibiotics into exodontia wounds.
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Accession number;00A0771318
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| Title;Study on penetration of oral antibiotics into exodontia wounds. |
| Author;
YOSHII TAKASHI
(Hyogokenshokuinkenkokanrise)
YOSHIKAWA TOMOHIRO
(Kobe Univ., Sch. of Med.)
YOSHIOKA AYUMI
(Kobe Univ., Sch. of Med.)
FURUDOI SHUNGO
(Kobe Univ., Sch. of Med.)
KOMORI TAKAHIDE
(Kobe Univ., Sch. of Med.)
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Journal Title;Japanese Journal of Chemotherapy
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Journal Code:F0608A
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ISSN:1340-7007
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VOL.48;NO.7;PAGE.541-544(2000)
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| Figure&Table&Reference;FIG.6, TBL.2, REF.18 |
| Pub. Country;Japan |
| Language;Japanese |
| Abstract;To evaluate the effectiveness of prophylaxis of infection after tooth extraction, antibiotic concentrations in exodontia wounds were determined after talampicillin (TAPC, 500 mg), cefaclor (CCL, 500 mg), and cefteram pivoxil (CFTM-PI, 200 mg) were given orally. The percentage of patients whose concentrations were higher than the MIC80 value against Streptococcus sp., which are frequently detected in oral infections, was 83.3-100% for TAPC at 60-360 min, 33.3-64.3% for CCL at 60-180 min, and 80.0-100% for CFTM-PI at 60-480 min. These findings indicate that TAPC or CFTM-PI is more reliable for prophylaxis. For effective prophylaxis, TAPC should be given about 60 min preoperatively and CFTM-PI about 60-120 min preoperatively. (author abst.) |
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