A Patient of Short Stature with Normal GH Secretion, but a Low Serum IGF-I Level.
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Accession number;00A0416129
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| Title;A Patient of Short Stature with Normal GH Secretion, but a Low Serum IGF-I Level. |
| Author;
MOCHIZUKI D
(Teikyo Univ. School Of Medicine, Tokyo, Jpn)
KODAMA H
(Teikyo Univ. School Of Medicine, Tokyo, Jpn)
KUBOTA K
(Teikyo Univ. School Of Medicine, Tokyo, Jpn)
MORI Y
(Teikyo Univ. School Of Medicine, Tokyo, Jpn)
NAKAMOTO N
(Teikyo Univ. School Of Medicine, Tokyo, Jpn)
KOBAYASHI M
(Teikyo Univ. School Of Medicine, Tokyo, Jpn)
YANAGAWA Y
(Teikyo Univ. School Of Medicine, Tokyo, Jpn)
KAJI M
(Shizuoka Children's Hospital)
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Journal Title;Endocr J
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Journal Code:F0625A
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ISSN:0918-8959
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VOL.47;NO.Supplement;PAGE.S125-S127(2000)
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| Figure&Table&Reference;FIG.2, TBL.1, REF.5 |
| Pub. Country;Japan |
| Language;English |
| Abstract;We report the case of a 7-year-old patient of short stature who had normal GH secretion, but a very low serum IGF-I level. On admittance, his height and weight were 102.2cm (-3.8S.D.) and 15.7kg (-1.8S.D)., respectively. His bone age was 2 years and 8 months. The serum GH responses to insulin, glucagon and L-dopa were all normal. GH secretion during sleep was also normal, but the serum IGF-I level was very low (29ng/ml). The serum IGF-I level was greatly increased by the administration of GH. No mutation was detected in the GH-1 gene. His height velocity was noticeably improved by GH treatment. (author abst.) |
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