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Accession number;00A0678472
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| Title;Four Cases of Pure Easily Falling Syndrome (PEFS) Showing a Symptom of Prone to Falling without Akinesia nor Rigidity. A Newly Proposed Concept. |
| Author;
YUASA TATSUHIKO
(Kokuritsu Seishin Shinkei Senta Konodai Byoin)
NEMOTO HIDEAKI
(Kokuritsu Seishin Shinkei Senta Konodai Byoin)
YOSHINO HIDE
(Kokuritsu Seishin Shinkei Senta Konodai Byoin)
NISHIMIYA JIN
(Kokuritsu Seishin Shinkei Senta Konodai Byoin)
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Journal Title;Japanese Journal of National Medical Services
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Journal Code:F0707A
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ISSN:0021-1699
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VOL.54;NO.6;PAGE.270-274(2000)
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| Figure&Table&Reference;FIG.1, TBL.3, REF.6 |
| Pub. Country;Japan |
| Language;Japanese |
| Abstract;Rigidity, tremor and akinesia are three main motor symptoms of Parkinson's disease. On the other hand some patients show an isolated akinesia without rigidity or tremor, being diagnosed as having pure akinesia. In this article we will present four patients with an isolated symptom of postural reflex disturbance, causing the tendency to fall backwards. We propose the term 'pure easily falling syndrome' (PEFS) to describe this special state, beside pure akinesia. Although the etiology of PEFS and/or the neurophysiological mechanism of falling of this type are yet to be resolved, this syndrome may be related to the some kind of neurodegenerative diseases, like progressive supranuclear palsy (PSP), pallido-nigro-Luysian atrophy (PNLA), striato-nigral degeneration (SND), pure akinesia and so on. The concept of PEFS may give us a potential tool to diagnose and evaluate the easy falling syndrome as an important initial sign of some underlying neurodegenerative disorders, and allow us to design a program for the treatment of PEFS patients. We also must keep following up the clinical course of the PEFS patients in order to clarify the disease process and the etiology. (author abst.) |
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